Targeted Therapeutics Research Award
Funded equally by LUNGevity Foundation and Joan's Legacy
Wenrui Duan, PhD
Ohio State University
Columbus
OH
The p53 gene can stop cells from becoming cancerous. It is mutated in non-small cell lung cancer, allowing cancer cells to grow in an uncontrolled manner. Dr. Duan is evaluating whether a new type of targeted therapy called PRIMA-1, used alone or in combination with other chemotherapies such as cisplatin, can stop the growth of non-small cell lung cancer cells.