A Novel Small Molecule Inhibitor of Protein Kinase C iota for the Treatment of Lung Cancer

Targeted Therapeutics Research Award
Funded equally by LUNGevity Foundation and American Lung Association National Office
Alan Patrick Fields, PhD
Mayo Clinic Jacksonville
Jacksonville
FL

Dr. Fields is generating pre-clinical data to support a clinical trial of a novel compound, autothiomalate (ATM), for the treatment of lung cancer. ATM, which is FDA-approved for rheumatoid arthritis, exhibits anti-cancer activity against non-small cell lung cancer (NSCLC) in preclinical studies.