Functional Heterogeneiety of Osteopontin Isoforms in Lung Cancer

Targeted Therapeutics Research Award
Funded equally by LUNGevity Foundation and the American Thoracic Society
Jessica Scott Donington, MD
NYU School of Medicine
New York
NY

The protein osteopontin plays a significant role in the malignant potential of numerous types of cancer, including lung cancer. There are three distinct forms of this protein in humans. Dr. Donington is studying how the individual forms play significantly different roles in determining the invasive metastatic potential in lung cancer.