Estrogen enhances the carcinogenic effects of the nicotine derivative NNK

Targeted Therapeutics Research Award
Funded equally by LUNGevity Foundation and the National Lung Cancer Partnership
Hildegard M. Schuller, DVM, PhD
University of Tennessee
Knoxville
TN

NNK is a powerful nicotine-derived carcinogen. Dr. Schuller is determining the exact role of estrogen in tumors caused by NNK. This understanding will provide new targets for the early diagnosis, prevention, and therapy of lung cancer in women.