Uncovering Molecular Markers of Hedgehog Antagonist Sensitive Lung Cancer
Targeted Therapeutics Research Award
Funded equally by LUNGevity Foundation and the American Lung Association
David J. Robbins, PhD
Dartmouth University Medical School
Hanover
NH
The Hedgehog (Hh) signaling pathway is active in both small cell and non-small cell lung cancer and provides a “don’t stop growing” signal to cancer cells. Dr. Robbins is working to identify and validate a panel of biomarkers that can be used to determine whether the lung cancer is sensitive to drugs that stop Hh signaling.
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