Profiling the phenotype of tumor derived stromal fibroblasts

Fibroblasts are cells found in different tissues of the body, including lung tissue. Dr. Arenberg is studying differences in the types of proteins made by tumor-derived lung fibroblast cells and by normal lung fibroblast cells. With an understanding of which proteins make a tumor-derived fibroblast behave in such a way as to promote tumor growth and spread, there is potential to therapeutically target them.