Activating phagocytosis to inhibit small cell lung carcinoma

Julien Sage, PhD
Stanford University
Stanford
Irving Weissman, MD
Stanford University
Stanford
CA
Drs. Sage and Weissman will test a new immunotherapy to boost the arsenal of immune cells to combat SCLC. They will work to disable a protein on the cancer cells that inhibits macrophages, a type of immune cell that can engulf and destroy cancer cells. This will boost the killing capacity of macrophages and recruit more immune cells to the area by the tumor.